Understanding HIV Biology for the Development of New Therapeutic Strategies

The Torbett Lab studies HIV entry, evolution, and assembly at the genomic, biochemical and structural levels, as well as human hematopoietic stem cell resistance of HIV lentiviral vector entry.

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May 17th, 2024
Torbett Lab Undergrads Lidiia Gagarina and Rithika Sivakumar present posters at the 2024 Undergraduate Research Symposium. UW Post-Baccalaureate Fellow Corinne Thomas presents at the “Pathogens and Host Cells” Oral Session. Congratulations!

May 9th, 2024
The Torbett Lab congratulates Christian Gallardo for his New Investigator Award from the UW/Fred Hutch CFAR. The title of his two-year project is “Discovery of Isoform-specific HIV-1 vRNA structured motifs via single molecule long-read sequencing”.

May 9th, 2024
Chet Ojha and Craig Schindewolf present a poster titled “B cell Production of the eCD4-Ig-Knob-in Hole-Reversed HIV-1 Immunoadhesin in Humanized NBSGW Mice” at the 27th Annual Meeting of the American Society of Gene & Cell Therapy.

April 22nd, 2024
The Torbett Lab moves to Building Cure at the Seattle Children’s Research Institute Downtown Campus.

January 8th, 2024
The Torbett Lab welcomes Kurt Berckmueller who is joining us as a Postdoctoral Fellow. Welcome to SCRI!!

October 19th, 2023
The Torbett Lab congratulates Shiyi Wang for her successful Doctoral Dissertation Defense titled “HIV evolution during ART failures unveiled using long-read sequencing and bioinformatics tools”. Cheers and best wishes Dr. Wang!

August 1st, 2023
The Torbett Lab welcomes Corinne Thomas and Jessica Albert who will be respectively joining as a UW Prep Fellow and Research Technician.

May 25th, 2023
Christian Gallardo gave an oral presentation at the “Latency” session at the 2023 Retroviruses Meeting at Cold Spring Harbor Laboratory reporting on his studies developing quantitative full-length sequencing approaches to interrogate the HIV-1 transcriptome in primary cell derived models of latency.

 

May 19th, 2023
Congratulations to Mariam Khan and Trisha Yu for presenting their work at the 2023 UW Undergraduate Research Symposium. Trisha’s work focused on the validation of an HIV-1 Gag proximal protein for its role in phenotypic variance in differentiated THP-1 cells. Mariam’s work focused on the role of HK-3 on cell viability after differentiation. Congrats for a job well done!

March 20th, 2023
Congratulations to the Torbett Lab and close collaborators at the Routh Lab for their manuscript “ViReMa: a virus recombination mapper of next-generation sequencing data characterizes diverse recombinant viral nucleic acids” now published in GigaScience!

March 9th, 2023
Congratulations to Christian Gallardo on being awarded a Phase 1 Technology Commercialization Grant from the Washington Research Foundation for his project titled “Improving and simplifying high throughput RNA sequencing with CASPR, a novel reagent class“.

February 10th, 2023
Congratulations to Eirini Vamva and Stosh Ozog for their manuscript “A lentiviral vector B cell gene therapy platform for the delivery of the anti-HIV-1 eCD4-Ig-Knob-in-Hole-Reversed immunoadhesin”, now published in Molecular Therapy-Methods & Clinical Development (Cell Press). Many thanks to co-authors and collaborators at the Farzan, Rawlings, Zwick, and James Labs.

February 7th, 2023
The Torbett Lab welcomes Dr. Tai-Wei Li, and Dr. Craig Schindewolf who join the lab as Postdoctoral Fellows.

January 19th, 2023
Torbett Lab Members attend the B-HIVE Center Face to Face Meeting at the Emory Conference Center in Atlanta, GA. Mia Faerch, Chet Ohja, and Jade Wolff present posters of their work and engage in fruitful discussions with collaborators. Christian Gallardo chairs “Sequencing and Bioinformatics” session.