Understanding HIV Biology for the Development of New Therapeutic Strategies

The Torbett Lab studies HIV entry, evolution, and assembly at the genomic, biochemical and structural levels, as well as human hematopoietic stem cell resistance of HIV lentiviral vector entry.


October  19th, 2023
The Torbett Lab congratulates Shiyi Wang for her successful Doctoral Dissertation Defense titled “HIV evolution during ART failures unveiled using long-read sequencing and bioinformatics tools”. Cheers and best wishes Dr. Wang!

August 1st, 2023
The Torbett Lab welcomes Corinne Thomas and Jessica Albert who will be respectively joining as a UW Prep Fellow and Research Technician.

May 25th, 2023
Christian Gallardo gave an oral presentation at the “Latency” session at the 2023 Retroviruses Meeting at Cold Spring Harbor Laboratory reporting on his studies developing quantitative full-length sequencing approaches to interrogate the HIV-1 transcriptome in primary cell derived models of latency.


May 19th, 2023
Congratulations to Mariam Khan and Trisha Yu for presenting their work at the 2023 UW Undergraduate Research Symposium. Trisha’s work focused on the validation of an HIV-1 Gag proximal protein for its role in phenotypic variance in differentiated THP-1 cells. Mariam’s work focused on the role of HK-3 on cell viability after differentiation. Congrats for a job well done!

March 20th, 2023
Congratulations to the Torbett Lab and close collaborators at the Routh Lab for their manuscript “ViReMa: a virus recombination mapper of next-generation sequencing data characterizes diverse recombinant viral nucleic acids” now published in GigaScience!

March 9th, 2023
Congratulations to Christian Gallardo on being awarded a Phase 1 Technology Commercialization Grant from the Washington Research Foundation for his project titled “Improving and simplifying high throughput RNA sequencing with CASPR, a novel reagent class“.

February 10th, 2023
Congratulations to Eirini Vamva and Stosh Ozog for their manuscript “A lentiviral vector B cell gene therapy platform for the delivery of the anti-HIV-1 eCD4-Ig-Knob-in-Hole-Reversed immunoadhesin”, now published in Molecular Therapy-Methods & Clinical Development (Cell Press). Many thanks to co-authors and collaborators at the Farzan, Rawlings, Zwick, and James Labs.

February 7th, 2023
The Torbett Lab welcomes Dr. Tai-Wei Li, and Dr. Craig Schindewolf who join the lab as Postdoctoral Fellows.

January 19th, 2023
Torbett Lab Members attend the B-HIVE Center Face to Face Meeting at the Emory Conference Center in Atlanta, GA. Mia Faerch, Chet Ohja, and Jade Wolff present posters of their work and engage in fruitful discussions with collaborators. Christian Gallardo chairs “Sequencing and Bioinformatics” session.

December 22nd, 2022
Congratulations to Christian Gallardo and collaborators at the Sarafianos Lab for their manuscript “Activation of HIV-1 proviruses increases downstream chromatin accessibility” published in iScience.

October 8th, 2022
Bruce Torbett, Christian Gallardo, and Shiyi Wang present their work at the Twenty-Sixth West Coast Retrovirus Meeting in Palm Springs.

August 10th, 2022
Dr. Mia Faerch joins the Torbett Lab as a Staff Scientist. Dr. Faerch brings experience in protein biochemistry and biophysics, and will be involved in work to delineate interactions between HIV and host proteins, along with studies on small molecule binding to viral proteins.

July 7th, 2022
Congratulations to Dr. Bruce Torbett on his $29M award from NIH/NIAID to establish and support the Behavior of HIV In Viral Environments (B-HIVE) Center, a multi-institutional program comprising 31 leading HIV researchers at 15 U.S. institutions and one in England. One of six funded centers nationally, B-HIVE is a highly collaborative project that will study HIV at the atomic, genomic and biological level.

June 23rd, 2022
Congratulations to Christian Gallardo for his manuscript “Selective ablation of 3′ RNA ends and processive RTs facilitate direct cDNA sequencing of full-length host cell and viral transcripts”, published in Nucleic Acids Research. Thanks to co-authors and close collaborators at the Routh Lab at UTMB.

June 21st, 2022
Dr. Chet Ojha joins the Torbett Lab as a Staff Scientist. Dr. Ojha brings breadth and depth of experience in virology, and will be involved in studies on the effect of opioids on HIV entry, and in work related to lentiviral vector gene delivery.